If you are one of the millions of Americans looking for the best CBD cream for pain management to help you achieve pain relief, you may be wondering: How does CBD stack up against traditional medication in clinical trials?

The following clinical trials put CBD extract to the test and indicate an enormous potential in utilizing CBD oil for chronic pain, the symptoms of epilepsy, and the treatment of addiction.

1. CBD and Epilepsy

In 2018, the FDA approved the very first cannabis-based medication for the treatment of the life-threatening epileptic seizures experienced by children with Lennox-Gastaut Syndrome (LGS) and Dravet Syndrome. The drug, called Epidiolex, was approved for use by children ages two years and up.

Many children with Dravet Syndrome and LGS experience symptoms that do not react to traditional medications. In the multinational, multicenter clinical trials that were undertaken across the US to discern whether CBD might be a potential therapeutic treatment for such conditions, however, researchers found that instances of seizures were reduced by nearly 39% for participants in the placebo-controlled, double-blind studies.

Based on these findings, the drug was then approved by the FDA later that year. This represents a significant milestone in the treatment of childhood seizures and mitigating their detrimental impact on a child’s physical, mental, and emotional development.


2. CBD for Pain

CBD for Pain

One of the most popular forms of CBD treatment in the United States in the use of a topical ointment for chronic, acute, and hard-to-treat pain symptoms.

Topical CBD creams contain CBD extract in amounts that vary according to the manufacturer and the extent of pain. This can the mild symptoms of muscle soreness experienced by athletes to the severe and hard-to-treat symptoms of chronic pain.

Acute and chronic pain conditions in the US and the rest of the world are becoming an increasingly persistent and pressing matter as aging populations from prior manufacture- and labor-intensive societies develop debilitating pain conditions in their old age.

This is one of the many reasons that CBD is currently undergoing clinical testing for its pain-reducing implications. One such study, published in the European Journal of Pain, found that the topical application of a CBD-based ointment reduced both inflammation and the pain-related behaviors associated with arthritis in clinical testing.

In another study published by the Journal of Experimental Medicine, researchers found that CBD treatments effectively suppressed the typically hard-to-treat symptoms of inflammatory and neuropathic pain conditions.

When it comes to finding the best CBD cream for pain, look for responsible manufacturers that practice transparent labeling and sourcing information. This is the best way to ensure the CBD pain relief rub you choose contains no harmful additives and is ethically sourced from organic, hemp-only sources.

3. CBD and Addiction

Finally, CBD treatments have been indicated as a potential therapeutic device for reducing opioid use amongst adults who experience issues with chronic pain.

Through various animal studies, researchers have found that CBD can work to modulate the neuronal circuits that control addictive behaviors and impact the intoxication and relapse phases of the addiction cycle. CBD may also help to mitigate the symptoms of the phase in combination with other medications.

While more human studies are needed, and research is ongoing, the possible implications are promising. So much so, that the NIH recently granted a $3.8 million grant for a five-year study that will examine the use of medical marijuana for reducing opioid use among participants with chronic pain symptoms.

The Final Word

As with any medical treatment, clinical trials are a critical aspect of developing new treatments that offer healthier, more natural avenues to relief.

Though clinical trials concerning the use of hemp oil for pain, epilepsy, anxiety, addiction, and a number of other medical issues continues, initial trials indicate that CBD may be a promising therapeutic treatment for the millions of Americans who suffer every day.